small studies and large gaps
CJC-1295 raises growth hormone and insulin-like growth factor 1.
This page covers the long and short forms. It explains insulin-like growth factor 1, a liver-made hormone, and the safety gaps.

The long form stays in blood much longer
CJC-1295 is a lab-made peptide, a short chain built from protein parts, that copies a body message and makes the growth gland release more growth hormone into your blood. Here you can compare its long and short forms.
The peptide copies a body hormone that starts growth hormone release. That hormone speaks to a small growth gland under your brain.
The long form carries an added hook called DAC. The hook holds the peptide to albumin, a common blood protein.
In healthy adults, the long form stayed in blood for 5.8–8.1 days [1]. The short form left within minutes or hours [1].
That time gap matters because the long form may remain after the shot day. Neither form of CJC-1295 has approval for use in people.
No long human safety test has been done [1]. The small studies only tell us about short-term blood changes.
CJC-1295 raised blood-test hormones in small studies
Healthy 20-to-40-year-old men took part in one small study that watched their blood for a week and checked it again later, but did not test whether they felt better. Each man got one shot under the skin.
The amount was 60 or 90 micrograms for each kilogram of body weight. A microgram is a millionth of a gram, and heavier men received more.
Growth hormone first reached about 7.5-fold its starting level, or seven and a half times as high [3]. One week later, the average level was roughly 46% higher.
The liver-made hormone, insulin-like growth factor 1, was roughly 45% higher. The men's growth hormone still rose and fell in its usual waves.
The drug didn't turn that rise and fall into a steady level. Another study used 30 or 60 micrograms for each kilogram of body weight.
In that study, growth hormone stayed higher for at least six days [1]. Insulin-like growth factor 1 stayed higher from nine through eleven days.
Those insulin-like growth factor 1 blood changes don't prove better strength, sleep, or healing. No long test in healthy adults checked those hoped-for results.
You can read what happened in the human tests. The growth hormone and insulin-like growth factor 1 steps and study amounts pages explain the blood tests.
CJC-1295 is a peptide, not a muscle-building steroid
CJC-1295 is a peptide, which means a short chain made from protein parts. It isn't a steroid.
The chain has 29 parts. Scientists changed four parts so the body wouldn't cut it apart as fast [2].
The paper numbers the changed parts as 2, 8, 15 and 27. Those numbers only show where the changes sit.
The long form adds a hook that holds albumin in the blood [2]. That common blood protein carries the peptide much longer.
The growth gland then releases your own growth hormone. Other drugs called tesamorelin and sermorelin use the same body message.
The peptide doesn't work like a muscle-building steroid. A steroid acts through a different part of the body.
Start with the answer you need most
You may want the short answer about the hormones first. You may instead need to know why the two forms last so differently.
- What does CJC-1295 do? One shot raised growth hormone about 46% and insulin-like growth factor 1 about 45% in healthy men after a week [3].
- What is CJC-1295? It's a lab-made peptide with four changes that slow the body's breakdown of it [2].
The long form joins a blood protein and stays for several days. The short form, called Modified GRF 1-29, lacks that hook and leaves much sooner.
That lab name means a changed copy of one short body hormone. Its effect on insulin-like growth factor 1 also ends sooner.
The growth hormone and insulin-like growth factor 1 steps explain what happens next. The risk answers mark the gaps in safety knowledge.
The full paper list names each source. The form comparison keeps the long and short forms apart.
Personal reports do not prove a benefit
The CJC-1295 effects page keeps personal accounts apart from blood-test findings. You'll also see which hoped-for changes no controlled trial has checked.